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    PopAffiliator: online calculator for individual affiliation to a major population group based on 17 autosomal short tandem repeat genotype profile.

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    Abstract
    Because of their sensitivity and high level of discrimination, short tandem repeat (STR) maker systems are currently the method of choice in routine forensic casework and data banking, usually in multiplexes up to 15–17 loci. Constraints related to sample amount and quality, frequently encountered in forensic casework, will not allow to change this picture in the near future, notwithstanding the technological developments. In this study, we present a free online calculator named PopAffiliator (http://cracs.fc.up.pt/popaffiliator) for individual population affiliation in the three main population groups, Eurasian, East Asian and sub-Saharan African, based on genotype profiles for the common set of STRs used in forensics. This calculator performs affiliation based on a model constructed using machine learning techniques. The model was constructed using a data set of approximately fifteen thousand individuals collected for this work. The accuracy of individual population affiliation is approximately 86%, showing that the common set of STRs routinely used in forensics provide a considerable amount of information for population assignment, in addition to being excellent for individual identification.
    URI
    http://hdl.handle.net/10642/472
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    • HV - Department of Life Sciences and Health
    Date
    2010-06-16
    Author
    Pereira, Luisa
    Alshamali, Farida
    Andreassen, Rune
    Ballard, Ruth
    Chantratita, Wasun
    Cho, Nam Soo
    Coudray, Clotilde
    Dugoujon, Jean-Michel
    Espinoza, Marta
    González-Andrade, Fabricio
    Hadi, Sibte
    Immel, Uta-Dorothee
    Jeran, Nina
    Havas, Dubravka
    Marian, Catalin
    Gonzales-Martin, Antonio
    Mertens, Gerd
    Parson, Walther
    Perone, Carlos
    Prieto, Lourdes
    Takeshita, Haruo
    Villalobos, Héctor Rangel
    Zeng, Zhaoshu
    Camacho, Rui
    Fonseca, Nuno A.
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