Now showing items 1-20 of 22

    • Adherence to response-guided pegylated interferon and ribavirin for people who inject drugs with hepatitis C virus genotype 2/3 infection: The ACTIVATE study 

      Cunningham, Evan B; Hajarizadeh, Behzad; Dalgard, Olav; Amin, Janaki; Hellard, Margaret; Foster, Graham R; Bruggmann, Philip; Conway, Brian; Backmund, Markus; Robaeys, Geert; Swan, Tracy; Marks, Philippa S; Quiene, Sophie; Applegate, Tanya L; Weltman, Martin; Shaw, David; Dunlop, Adrian; Bruneau, Julie; Midgard, Håvard; Bourgeois, Stefan; Thurnheer, Maria Christine; Dore, Gregory J; Grebely, Jason; Shaw, Ineke; Siriragavan, Sharmila; Horschik, Tina; Sharma, Shawn; Eevers, Anita; Andreassen, Jessica; Melkeraaen, Ingunn; Widder, Nicole; Lesneuck, Kristof; Kotsoros, Barbara; Hazelwood, Susan; Holland, Rohan; Axten, David; Von Bibra, Sally; Powis, Jeff; Mason, Kate; Ryder, Stephen; Jack, Kate; Scheidegger, Claude; Huber, Christine; Ferguson, Catherine; Staehelin, Cornelia; Lacalamita, Melanie; Fragomeli, Vincenzo; Sevehon, Alison (BMC Springer, 2017-06-13)
      Background The aims of this analysis were to investigate treatment completion and adherence among people with ongoing injecting drug use or receiving opioid substitution therapy (OST) in a study of response-guided therapy ...
    • Biomarkers in subtypes of mild cognitive impairment and subjective cognitive decline 

      Eliassen, Carl F Andestad; Reinvang, Ivar; Selnes, Per; Grambaite, Ramune; Fladby, Tormod; Hessen, Erik (Wiley, 2017-07-28)
      Objectives Preclinical Alzheimers disease (AD) patients may or may not show cognitive impairment on testing. AD biomarkers are central to the identification of those at low, intermediate, or high risk of later dementia ...
    • Bone turnover markers are associated with bone density, but not with fracture in end stage kidney disease: a cross-sectional study 

      Jørgensen, Hanne Skou; Winther, Simon; Bøttcher, Morten; Hauge, Ellen Margrethe; Rejnmark, Lars; Svensson, My Hanna Sofie; Ivarsen, Per (BMC Springer, 2017-09-06)
      Background Fracture risk is increased in chronic kidney disease (CKD), but assessment of bone fragility remains controversial in these patients. This study investigated the associations between bone turnover markers, bone ...
    • Cardiopulmonary exercise test and PaO2 in evaluation of pulmonary hypertension in COPD 

      Skjørten, Ingunn; Hilde, Janne Mykland; Melsom, Morten Nissen; Hisdal, Jonny; Hansteen, Viggo; Steine, Kjetil; Humerfelt, Sjur (Dove Medical Press, 2017-08-26)
      Background: Exercise tolerance decreases as COPD progresses. Pulmonary hypertension (PH) is common in COPD and may reduce performance further. COPD patients with and without PH could potentially be identified by cardiopulmonary ...
    • Clues for early detection of autoimmune Addison's disease - myths and realities 

      Sævik, Åse Bjorvatn; Akerman, A.-K.; Grønning, Kaja; Nermoen, Ingrid; Valland, Susanna Fonneland; Finnes, Trine Elisabeth; Isaksson, M; Dahlqvist, P; Bergthorsdottir, R; Ekwall, O; Skov, J; Nedrebø, Bjørn Gunnar; Hulting, A.-L.; Wahlberg, J; Svartberg, Johan; Höybye, C; Bleskestad, Inger Hjørdis; Jørgensen, Anders Palmstrøm; Kämpe, Olle; Øksnes, Marianne; Bensing, S; Husebye, Eystein Sverre (Wiley, 2017-11-03)
      BACKGROUND: Early detection of autoimmune Addison's disease (AAD) is important as delay in diagnosis may result in a life-threatening adrenal crisis and death. The classical clinical picture of untreated AAD is well-described, ...
    • Cognitive deficits in chronic stroke patients: neuropsychological assessment, depression, and self-reports 

      Nakling, Arne; Årsland, Dag; Næss, Halvor; Wollschläger, Daniel; Fladby, Tormod; Hofstad, Håkon; Eike, Wehling (Karger, 2017)
      Background: Following stroke, clinicians are challenged to detect and untangle symptoms of cognitive dysfunction and mood disorders. Additionally, they need to evaluate the informative value of self-reports to identify ...
    • Early introduction of oral paricalcitol in renal transplant recipients. An open-label randomized study 

      Pihlstrøm, Hege; Gatti, Francesca; Hammarström, Clara Louise; Eide, Ivar Anders; Kasprzycka, Monika; Wang, Junbai; Haraldsen, Guttorm; Svensson, My Hanna Sofia; Midtvedt, Karsten; Mjøen, Geir; Dahle, Dag Olav; Hartmann, Anders; Holdaas, Hallvard (Wiley, 2017-04-24)
      In stable renal transplant recipients with hyperparathyroidism, previous studies have indicated that vitamin D agonist treatment might have anti-proteinuric effects. Animal studies indicate possible anti-fibrotic and ...
    • Efficacy of response-guided directly observed pegylated interferon and self-administered ribavirin for people who inject drugs with hepatitis C virus genotype 2/3 infection: The ACTIVATE study 

      Grebely, Jason; Dalgard, Olav; Cunningham, Evan B; Hajarizadeh, Behzad; Foster, Graham R; Bruggmann, Philip; Conway, Brian; Backmund, Markus; Robaeys, Geert; Swan, Tracy; Amin, Janaki; Marks, Philippa S; Quiene, Sophie; Applegate, Tanya L; Weltman, Martin; Shaw, David; Dunlop, Adrian; Hellard, Margaret; Bruneau, Julie; Midgard, Håvard; Bourgeois, Stefan; Staehelin, Cornelia; Dore, Gregory J (Elsevier, 2017-09)
      Background There are few data on treatment for hepatitis C virus (HCV) infection among people with ongoing injecting drug use. This study evaluated the efficacy of response-guided therapy for chronic HCV genotypes 2/3 ...
    • Extending XNAT platform with an incremental semantic framework 

      Reina, Santiago Timon; Rincón, Mariano; Martinez-Tomás, Rafael (Frontiers Media S.A., 2017-08-31)
      Informatics increases the yield from neuroscience due to improved data. Data sharing and accessibility enable joint efforts between different research groups, as well as replication studies, pivotal for progress in the ...
    • Finasteride treatment and male breast cancer: a register-based cohort study in four Nordic countries 

      Meijer, Mathias; Thygesen, Lau Caspar; Green, Anders; Emneus, Martha; Brasso, Klaus; Iversen, Peter; Pukkalo, Eero; Bolin, Kristian; Stavem, Knut; Ersbøll, Annette Kjær (Wiley, 2017-12-13)
      A potential link has been suggested between dispensed finasteride and increased risk of male breast cancer (MBC). Due to the rare occurrence of MBC, it remains to be established if such a relationship exists. The purpose ...
    • Global prevalence and genotype distribution of hepatitis C virus infection in 2015: a modelling study 

      Blach, Sarah; Zeuzem, Stefan; Manns, Michael; Altraif, Ibrahim; Duberg, Ann-Sofi; Muljono, David H; Waked, Imam; Alavian, Seyed M; Lee, Mei-Hsuan; Negro, Francesco; Abaalkhail, Faisal; Abdou, Ahmed; Abdulla, Maheeba; Rached, Antoine Abou; Aho, Inka; Akarca, Ulus; Ghazzawi, Imad Al; Kaabi, Saad Al; Lawati, Faryal Al; Namaani, Khalid Al; Serkal, Youssif Al; Al-Busafi, Said A; Al-Dabal, Layla; Aleman, Soo; Alghamdi, Abdullah S; Aljumah, Abdulrahman A; Al-Romaihi, Hamad E; Andersson, Monique I; Arendt, Vic; Arkkila, Perttu; Assiri, Abdullah M; Baatarkhuu, Oidov; Bane, Abate; Ben-Ari, Ziv; Bergin, Colm; Bessone, Fernando; Bihl, Florian; Bizri, Abdul R; Blachier, Martin; Blasco, Antonio J; Mello, Carlos E Brandao; Bruggmann, Philip; Brunton, Cheryl R; Calinas, Filipe; Chan, Henry L Y; Chaudhry, Asad; Cheinquer, Hugo; Chen, Chien-Jen; Chien, Rong-Nan; Choi, Moon Seok; Christensen, Peer B; Chuang, Wan-Long; Chulanov, Vladimir; Cisneros, Laura; Clausen, Mette R; Cramp, Matthew E; Craxi, Antonio; Croes, Esther A; Dalgard, Olav (Elsevier, 2017-03)
      Background The 69th World Health Assembly approved the Global Health Sector Strategy to eliminate hepatitis C virus (HCV) infection by 2030, which can become a reality with the recent launch of direct acting antiviral ...
    • Impaired synaptic function is linked to cognition in Parkinson's disease 

      Selnes, Per; Stav, Ane Løvli; Johansen, Krisztina Kunszt; Bjørnerud, Atle; Coello, Sebastien Christopher; Auning, Eirik; Kalheim, Lisa Flem; Almdahl, Ina Selseth; Hessen, Erik; Zetterberg, Henrik; Blennow, Kaj; Årsland, Dag; Fladby, Tormod (Wiley, 2017-08-31)
      Objective Cognitive impairment is frequent in Parkinson's disease, but the underlying mechanisms are insufficiently understood. Because cortical metabolism is reduced in Parkinson's disease and closely associated with ...
    • Morbidity outcomes after surgical aortic valve replacement 

      Auensen, Andreas; Hussain, Amjad Iqbal; Bendz, Bjørn; Aaberge, Lars; Falk, Ragnhild Sørum; Hansen, Marte; Bye, Eva; Andreassen, Johanna; Beitnes, Jan Otto; Rein, Kjell Arne; Pettersen, Kjell I; Gullestad, Lars (BMJ Publishing Group, 2017-04-13)
      Objective In patients with mild to moderate operative risk, surgical aortic valve replacement (SAVR) is still the preferred treatment for patients with severe symptomatic aortic stenosis (AS). Aiming to broaden the knowledge ...
    • Overall Survival in Renal Cell Carcinoma after Introduction of Targeted Therapies: A Norwegian Population-Based Study 

      Beisland, Christian; Johannesen, Tom Bjørge; Klepp, Olbjørn; Axcrona, Ulrika; Torgersen, Knut Martin; Kowalski, Jan; Solli, Oddvar; Sandin, Rickard; Oldenburg, Jan (Dove Medical Press, 2017-01-16)
      Background: This population-wide retrospective, non-interventional registry study assessed changes in overall survival (OS) and factors influencing OS in Norwegian patients with renal cell carcinoma (RCC). Methods: Two ...
    • Physical distress is associated with cardiovascular events in a high 

      Einvik, Gunnar; Ekeberg, Øivind; Klemsdal, Tor O; Sandvik, Leiv; Hjerkinn, Elsa M (BioMed Central, 2009-03-30)
      Background: Self-reported health perceptions such as physical distress and quality of life are suggested independent predictors of mortality and morbidity in patients with established cardiovascular disease. This study ...
    • Predictive value of C-reactive protein in patients treated with sunitinib for metastatic clear cell renal cell carcinoma 

      Pilskog, Martin; Beisland, Christian; Akslen, Lars A; Bostad, Leif; Haug, Åse; Heinrich, Daniel; Hjelle, Karin Margrethe; Straume, Oddbjørn (BMC Springer, 2017-08-31)
      Background Sunitinib has become mainstay first line treatment for patients with metastatic renal clear cell carcinoma (mRCC). Still, useful predictive markers of response are lacking and urgently needed for clinical ...
    • Research priorities to achieve universal access to hepatitis C prevention, management and direct-acting antiviral treatment among people who inject drugs. 

      Grebely, Jason; Bruneau, Julie; Lazarus, Jeffrey; Dalgard, Olav; Bruggmann, Philip; Treloar, Carla; Hickman, Matthew; Hellard, Margaret; Roberts, Teri; Crooks, Levinia; Midgard, Håvard; Larney, Sarah; Degenhardt, Louisa; Alho, Hannu; Byrne, Jude; Dillon, John F; Feld, Jordan J; Foster, Graham; Goldberg, David E; Lloyd, Andrew R; Reimer, Jens; Robaeys, Geert; Torrens, Marta; Wright, Nat; Maremmani, Icro; Norton, Brianna L; Litwin, Alain H; Dore, Gregory J (Elsevier, 2017-09)
      Globally, it is estimated that 71.1 million people have chronic hepatitis C virus (HCV) infection, including an estimated 7.5 million people who have recently injected drugs (PWID). There is an additional large, but ...
    • Sofosbuvir based treatment of chronic hepatitis C genotype 3 infections - a Scandinavian real-life study 

      Dalgard, Olav; Weiland, Ola; Noraberg, Geir; Karlsen, Lars Normann; Heggelund, Lars; Färkkilä, Martti; Balselv, Ulla; Berlard, Erika; Øvrehus, Anne; Kjær, Mette Skalshøi; Krarup, Henrik; Røge, Birgit Thorup; Hallager, Sofie; Madsen, Lone G; Laursen, Alex Lund; Lagging, Martin; Weis, Nina (PLOS, 2017-07-13)
      Background and aims Chronic hepatitis C virus (HCV) genotype 3 infection with advanced liver disease has emerged as the most challenging to treat. We retrospectively assessed the treatment outcome of sofosbuvir (SOF) based ...
    • Subjective cognitive impairment is a predominantly benign condition in memory clinic patients followed for 6 years: The Gothenburg-oslo MCI Study 

      Hessen, Erik; Eckerström, Marie; Nordlund, Arto; Almdahl, Ina; Stålhammar, Jacob; Bjerke, Maria; Eckerström, Carl; Göthlin, Mattias; Fladby, Tormod; Reinvang, Ivar; Wallin, Anders (Karger, 2017-02-02)
      Background/Aims: In the quest for prevention or treatment, there is a need to find early markers for preclinical dementia. This study observed memory clinic patients with subjective cognitive impairment (SCI) and normal ...
    • Two novel connexin32 mutations cause early onset X-linked Charcot-Marie-Tooth disease 

      Braathen, Geir Julius; Sand, Jette C.; Bukholm, Geir; Russell, Michael B. (BioMed Central, 2007-07-09)
      Background X-linked Charcot-Marie Tooth (CMT) is caused by mutations in the connexin32 gene that encodes a polypeptide which is arranged in hexameric array and form gap junctions. Methods We describe two novel ...