Now showing items 17-36 of 44

    • Fatigue is not associated with vitamin D deficiency in inflammatory bowel disease patients 

      Frigstad, Svein Oskar; Høivik, Marte Lie; Jahnsen, Jørgen; Småstuen, Milada Cvancarova; Grimstad, Tore; Berset, Ingrid Prytz; Huppertz-Hauss, Gert; Hovde, Øistein; Bernklev, Tomm; Moum, Bjørn; Jelsness-Jørgensen, Lars-Petter (Baishideng Publishing Group, 2018-08-07)
      AIM To investigate if vitamin D deficiency is associated with fatigue in patients with inflammatory bowel disease (IBD). METHODS IBD patients were recruited from nine hospitals in the southeastern and western regions ...
    • Finasteride treatment and male breast cancer: a register-based cohort study in four Nordic countries 

      Meijer, Mathias; Thygesen, Lau Caspar; Green, Anders; Emneus, Martha; Brasso, Klaus; Iversen, Peter; Pukkalo, Eero; Bolin, Kristian; Stavem, Knut; Ersbøll, Annette Kjær (Wiley, 2017-12-13)
      A potential link has been suggested between dispensed finasteride and increased risk of male breast cancer (MBC). Due to the rare occurrence of MBC, it remains to be established if such a relationship exists. The purpose ...
    • Global prevalence and genotype distribution of hepatitis C virus infection in 2015: a modelling study 

      Blach, Sarah; Zeuzem, Stefan; Manns, Michael; Altraif, Ibrahim; Duberg, Ann-Sofi; Muljono, David H; Waked, Imam; Alavian, Seyed M; Lee, Mei-Hsuan; Negro, Francesco; Abaalkhail, Faisal; Abdou, Ahmed; Abdulla, Maheeba; Rached, Antoine Abou; Aho, Inka; Akarca, Ulus; Ghazzawi, Imad Al; Kaabi, Saad Al; Lawati, Faryal Al; Namaani, Khalid Al; Serkal, Youssif Al; Al-Busafi, Said A; Al-Dabal, Layla; Aleman, Soo; Alghamdi, Abdullah S; Aljumah, Abdulrahman A; Al-Romaihi, Hamad E; Andersson, Monique I; Arendt, Vic; Arkkila, Perttu; Assiri, Abdullah M; Baatarkhuu, Oidov; Bane, Abate; Ben-Ari, Ziv; Bergin, Colm; Bessone, Fernando; Bihl, Florian; Bizri, Abdul R; Blachier, Martin; Blasco, Antonio J; Mello, Carlos E Brandao; Bruggmann, Philip; Brunton, Cheryl R; Calinas, Filipe; Chan, Henry L Y; Chaudhry, Asad; Cheinquer, Hugo; Chen, Chien-Jen; Chien, Rong-Nan; Choi, Moon Seok; Christensen, Peer B; Chuang, Wan-Long; Chulanov, Vladimir; Cisneros, Laura; Clausen, Mette R; Cramp, Matthew E; Craxi, Antonio; Croes, Esther A; Dalgard, Olav (Elsevier, 2017-03)
      Background The 69th World Health Assembly approved the Global Health Sector Strategy to eliminate hepatitis C virus (HCV) infection by 2030, which can become a reality with the recent launch of direct acting antiviral ...
    • Health status in subjects with suspected obstructive sleep apnea and comparison with a general population 

      Beiske, Kornelia Katalin; Stavem, Knut (Nature, 2018-04-03)
      The purpose of this study was to assess health status (HS) in patients with clinical suspicion of obstructive sleep apnea (OSA) in order to estimate the dose response relationship between HS and OSA severity, and to ...
    • Impaired synaptic function is linked to cognition in Parkinson's disease 

      Selnes, Per; Stav, Ane Løvli; Johansen, Krisztina Kunszt; Bjørnerud, Atle; Coello, Sebastien Christopher; Auning, Eirik; Kalheim, Lisa Flem; Almdahl, Ina Selseth; Hessen, Erik; Zetterberg, Henrik; Blennow, Kaj; Årsland, Dag; Fladby, Tormod (Wiley, 2017-08-31)
      Objective Cognitive impairment is frequent in Parkinson's disease, but the underlying mechanisms are insufficiently understood. Because cortical metabolism is reduced in Parkinson's disease and closely associated with ...
    • Inflammation and Mechanical Stress Stimulate Osteogenic Differentiation of Human Aortic Valve Interstitial Cells 

      Bogdanova, Mariia; Kostina, Aleksandra; Zihlavnikova, Katarina; Zabirnyk, Arsenii; Malashicheva, Anna; Stensløkken, Kåre-Olav; Sullivan, Gareth; Kaljusto, Mari-Liis; Kvitting, John Peder Escobar; Kostareva, Anna; Vaage, Ingvar Jarle; Rutkovskiy, Arkady (Frontiers Media, 2018-11-20)
      Background: Aortic valve calcification is an active proliferative process, where interstitial cells of the valve transform into either myofibroblasts or osteoblast-like cells causing valve deformation, thickening of cusps ...
    • Left ventricular biomechanics in professional football players 

      von Lueder, Thomas Gero; Hodt, Anders; Gjerdalen, Gard Filip; Steine, Kjetil (Wiley, 2017-04-04)
      Chronic exercise induces adaptive changes of left ventricular (LV) ejection and filling capacities which may be detected by novel speckle‐tracking echocardiography (STE) and tissue Doppler imaging (TDI)‐based techniques. ...
    • Morbidity outcomes after surgical aortic valve replacement 

      Auensen, Andreas; Hussain, Amjad Iqbal; Bendz, Bjørn; Aaberge, Lars; Falk, Ragnhild Sørum; Hansen, Marte; Bye, Eva; Andreassen, Johanna; Beitnes, Jan Otto; Rein, Kjell Arne; Pettersen, Kjell I; Gullestad, Lars (BMJ Publishing Group, 2017-04-13)
      Objective In patients with mild to moderate operative risk, surgical aortic valve replacement (SAVR) is still the preferred treatment for patients with severe symptomatic aortic stenosis (AS). Aiming to broaden the knowledge ...
    • NAD+ in aging: molecular mechanisms and translational implications 

      Fang, Evandro Fei; Lautrup, Sofie; Hou, Yujun; Demarest, Tyler G; Croteau, Deborah L; Mattson, Mark P; Bohr, Vilhelm A (Elsevier, 2017-10)
      AB The coenzyme NAD+ is critical in cellular bioenergetics and adaptive stress responses. Its depletion has emerged as a fundamental feature of aging that may predispose to a wide range of chronic diseases. Maintenance of ...
    • Novel biomarkers of cardiovascular disease: Applications in clinical practice 

      Lyngbakken, Magnus; Myhre, Peder Langeland; Røsjø, Helge; Omland, Torbjørn (Taylor & Francis, 2018-11-20)
      Measurement of biomarkers has revolutionized the work-up of patients with suspected cardiovascular disease. The most widely used contemporary cardiovascular biomarkers are the natriuretic peptides in the diagnosis and ...
    • Novel serum and bile protein markers predict primary sclerosing cholangitis disease severity and prognosis 

      Vesterhus, Mette; Holm, Anders; Hov, Johannes Espolin Roksund; Nygård, Ståle; Schrumpf, Erik; Melum, Espen; Thorbjørnsen, Liv Wenche; Paulsen, Vemund; Lundin, Knut Erik Aslaksen; Dale, Inge; Gilja, Odd Helge; Zweers, Serge J.; Vatn, Morten H.; Schaap, Frank G.; Jansen, Peter L. M.; Ueland, Thor; Røsjø, Helge; Moum, Bjørn; Ponsioen, Cyriel Y.; Boberg, Kirsten Muri; Färkkilä, Martti; Karlsen, Tom Hemming; Lund-Johansen, Fridtjof (Elsevier, 2017-02-02)
      Background & Aims Prognostic biomarkers are lacking in primary sclerosing cholangitis, hampering patient care and the development of therapy. We aimed to identify novel protein biomarkers of disease severity and prognosis ...
    • Overall Survival in Renal Cell Carcinoma after Introduction of Targeted Therapies: A Norwegian Population-Based Study 

      Beisland, Christian; Johannesen, Tom Bjørge; Klepp, Olbjørn; Axcrona, Ulrika; Torgersen, Knut Martin; Kowalski, Jan; Solli, Oddvar; Sandin, Rickard; Oldenburg, Jan (Dove Medical Press, 2017-01-16)
      Background: This population-wide retrospective, non-interventional registry study assessed changes in overall survival (OS) and factors influencing OS in Norwegian patients with renal cell carcinoma (RCC). Methods: Two ...
    • Patient knowledge on stroke risk factors, symptoms and treatment options 

      Faiz, Kashif Waqar; Sundseth, Antje; Thommessen, Bente; Rønning, Ole M. (Dove Medical Press, 2018-02-07)
      Background: Public campaigns focus primarily on stroke symptom and risk factor knowledge, but patients who correctly recognize stroke symptoms do not necessarily know the reason for urgent hospitalization. The aim of this ...
    • Physical distress is associated with cardiovascular events in a high 

      Einvik, Gunnar; Ekeberg, Øivind; Klemsdal, Tor O; Sandvik, Leiv; Hjerkinn, Elsa M (BioMed Central, 2009-03-30)
      Background: Self-reported health perceptions such as physical distress and quality of life are suggested independent predictors of mortality and morbidity in patients with established cardiovascular disease. This study ...
    • Policy responses to hepatitis C in the Nordic countries: Gaps and discrepant reporting in the Hep-Nordic study 

      Safreed-Harmon, Kelly; Hetherington, Kristina L.; Aleman, Soo; Alho, Hannu; Dalgard, Olav; Frisch, Tove; Gottfredsson, Magnus; Weis, Nina; Lazarus, Jeffrey V. (PLOS, 2018-01-30)
      Background and aims In the Nordic countries (Denmark, Finland, Iceland, Norway, Sweden), the prevalence of chronic hepatitis C virus (HCV) infection is relatively low in the general population, but is much higher among ...
    • Predictive value of C-reactive protein in patients treated with sunitinib for metastatic clear cell renal cell carcinoma 

      Pilskog, Martin; Beisland, Christian; Akslen, Lars A; Bostad, Leif; Haug, Åse; Heinrich, Daniel; Hjelle, Karin Margrethe; Straume, Oddbjørn (BMC Springer, 2017-08-31)
      Background Sunitinib has become mainstay first line treatment for patients with metastatic renal clear cell carcinoma (mRCC). Still, useful predictive markers of response are lacking and urgently needed for clinical ...
    • Prevalence of carotid plaque in a 63- to 65-Year-Old Norwegian cohort from the general population: The ACE (Akershus Cardiac Examination) 1950 study 

      Ihle-Hansen, Håkon; Vigen, Thea; Ihle-Hansen, Hege; Rønning, Ole M.; Berge, Trygve; Thommessen, Bente; Lyngbakken, Magnus; Orstad, Eivind Bjørkan; Enger, Steve; Nygård, Ståle; Røsjø, Helge; Tveit, Arnljot (Wiley, 2018-05-08)
      Background New data on extracranial carotid atherosclerosis are needed, as improved ultrasound techniques may detect more atherosclerosis, the definition of plaque has changed over the years, and better cardiovascular ...
    • Research priorities to achieve universal access to hepatitis C prevention, management and direct-acting antiviral treatment among people who inject drugs. 

      Grebely, Jason; Bruneau, Julie; Lazarus, Jeffrey; Dalgard, Olav; Bruggmann, Philip; Treloar, Carla; Hickman, Matthew; Hellard, Margaret; Roberts, Teri; Crooks, Levinia; Midgard, Håvard; Larney, Sarah; Degenhardt, Louisa; Alho, Hannu; Byrne, Jude; Dillon, John F; Feld, Jordan J; Foster, Graham; Goldberg, David E; Lloyd, Andrew R; Reimer, Jens; Robaeys, Geert; Torrens, Marta; Wright, Nat; Maremmani, Icro; Norton, Brianna L; Litwin, Alain H; Dore, Gregory J (Elsevier, 2017-09)
      Globally, it is estimated that 71.1 million people have chronic hepatitis C virus (HCV) infection, including an estimated 7.5 million people who have recently injected drugs (PWID). There is an additional large, but ...
    • Sofosbuvir and velpatasvir for hepatitis C virus infection in people with recent injection drug use (SIMPLIFY): an open-label, single-arm, phase 4, multicentre trial 

      Grebely, Jason; Dalgard, Olav; Conway, Brian; Cunningham, Evan B.; Bruggmann, Philip; Hajarizadeh, Behzad; Amin, Janaki; Bruneau, Julie; Hellard, Margaret; Litwin, Alain H.; Marks, Phillippa; Quiene, Sophie; Siriragavan, Sharmila; Applegate, Tanya L.; Swan, Tracy; Byrne, Jude; Lacalamita, Melanie; Dunlop, Adrian; Matthews, Gail V.; Powis, Jeff; Shaw, David; Thurnheer, Maria Christine; Weltmann, Martin; Kronborg, Ian; Cooper, Curtis; Feld, Jordan J.; Fraser, Chris; Dillon, John F.; Read, Phillip; Gane, Edward; Dore, Gregory J. (Elsevier, 2018-03)
      Background Despite revised guidelines that no longer exclude people who inject drugs (PWID) from treatment for hepatitis C virus (HCV) infection, many clinicians are reluctant to treat recent PWID. This study aimed to ...
    • Sofosbuvir based treatment of chronic hepatitis C genotype 3 infections - a Scandinavian real-life study 

      Dalgard, Olav; Weiland, Ola; Noraberg, Geir; Karlsen, Lars Normann; Heggelund, Lars; Färkkilä, Martti; Balselv, Ulla; Berlard, Erika; Øvrehus, Anne; Kjær, Mette Skalshøi; Krarup, Henrik; Røge, Birgit Thorup; Hallager, Sofie; Madsen, Lone G; Laursen, Alex Lund; Lagging, Martin; Weis, Nina (PLOS, 2017-07-13)
      Background and aims Chronic hepatitis C virus (HCV) genotype 3 infection with advanced liver disease has emerged as the most challenging to treat. We retrospectively assessed the treatment outcome of sofosbuvir (SOF) based ...