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dc.contributor.authorSygna, Karinen_US
dc.contributor.authorJohansen, Saforaen_US
dc.contributor.authorRuland, Corneliaen_US
dc.date.accessioned2016-02-24T09:48:41Z
dc.date.available2016-02-24T09:48:41Z
dc.date.issued2015en_US
dc.identifier.citationSygna, K., Johansen, S. & Ruland, C. (2015). Recruitment challenges in clinical research including cancer patients and their caregivers. A randomized controlled trial study and lessons learned. Trials, 16(428). doi: 10.1186/s13063-015-0948-yen_US
dc.identifier.issn1745-6215en_US
dc.identifier.otherFRIDAID 1265357en_US
dc.identifier.urihttp://hdl.handle.net/10642/3067
dc.description.abstractBackground: To test seven different strategies for recruitment in a randomized controlled trial, to report documented response data from each strategy, and to discuss recruitment challenges. Methods: We used 5 opt-in (potential participants have to do something active to contact or be contacted by the researcher) and 2 opt-out (potential participants have the option to decline being contacted about a study) recruitment strategies from February 2013 until July 2014 to contact 1562 cancer patient candidates for participation in a randomized controlled trial. For each of these cancer patients a caregiver was also invited to take part in the study. Results: Of the 1562 candidates, 22.6 % were ineligible on initial contact, 56.7 % declined to participate on initial contact, and 8.9 % agreed orally to participate but did not complete the enrollment. The 2 opt-out strategies, on-site recruitment and routine care letters recruitment, yielded the highest number of recruited participants with 79 dyads and 58 dyads respectively, constituting 42.7 % and 31.4 % of the total number of enrolled candidates. The 5 opt-in recruitment approaches yielded 49 dyads for the study. Almost half of these dyads were recruited using the approach termed “relying on providers at the hospital.” Conclusions: In this study, opt-out recruitment strategies appeared to be the most effectiveen_US
dc.language.isoengen_US
dc.publisherBioMed Centralen_US
dc.relation.ispartofseriesTrials;16(428)en_US
dc.subjectRecruitmenten_US
dc.subjectRecruitment challengesen_US
dc.subjectCancer patientsen_US
dc.subjectCaregiversen_US
dc.subjectClinical researchen_US
dc.subjectIntervention studyen_US
dc.titleRecruitment challenges in clinical research including cancer patients and their caregivers. A randomized controlled trial study and lessons learneden_US
dc.typeJournal articleen_US
dc.typePeer revieweden_US
dc.description.version© 2015 Sygna et al. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
dc.identifier.doihttp://dx.doi.org/10.1186/s13063-015-0948-y


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